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CD73 in aggressive basal cell carcinoma
This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...
Treatment of low-risk basal cell carcinoma and actinic
The first paper of this topic explored skin cancer recognition, patient education and sun safety. The second part focused on practical guidance for aesthetic nurses, should a patient present with a suspicious skin lesion. The author maintains that aesthetic nurses...
Extranodal NK/T cell lymphoma in the head and neck
The authors present a retrospective single institution review of patients with a very rare variant of non-Hodgkin lymphomas (NHL). They report on the occurrence, clinical course and outcomes of their patients with natural killer/T-cell lymphoma (NKTCL) nasal type. Sixty-three patients...Cord lining mesenchymal stem cell exosomal proteins and their effects on hair follicles
Umbilical cord lining (UCL) mesenchymal stem cells (MSC) produce proteins and growth factors that, when packaged into exosomes in fixed proportions, can stimulate repair and regeneration in recipient cells. The pleiotropic properties of UCL-MSC have been shown to be effective...
Outcomes of heavily pre-treated oral squamous cell carcinomas
Oral squamous cell carcinoma is one of the more common cancers worldwide. Surgery is the mainstay of treatment and often these patients have had adjuvant therapies. In spite of improving five year survival rates, local recurrent progressive disease is still...
Postoperative follow-up of oral squamous cell carcinoma: a new protocol
Oral and oropharyngeal cancers together are the sixth most common malignancy in the world, with an increasing incidence of oral squamous cell carcinoma (OSCC). The recurrence rate of OSCC is reported to be approximately 10-26%. About two-thirds of all recurrent...
PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...Stem cells in reconstructive surgery: a bright but cautious future
Regenerative medicine using stem cell technology is slowly becoming a reality in routine clinical practice especially in the field of tissue regeneration [1]. It is therefore not surprising that stem cell technology is starting to be of interest in reconstructive...Exosomes: everything you always wanted to know and questions to ask your exosome provider
This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. What are exosomes? Exosomes are just one subset of extracellular vesicles (EVs),...
Allogenic submandibular gland transplantation
The authors discuss and report success with an elegant but difficult solution to a difficult problem. Dry eyes are a difficult problem and incidence increases with age. It can lead to severe reduction in the quality of life of patients....
