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IgG4-related disease or Graves orbitopathy

This is a retrospective review of patients who had been diagnosed with both IgG4-related ophthalmic disease (IgG4-ROD) and Graves orbitopathy over a four-year period. Eight patients were identified. The diagnosis of IgG4-ROD was based on 10 or more IgG4+ plasma...

Congenital ptosis and astigmatism

This is a review of the effect of congenital ptosis surgery on refractive error. Seventy-one eyes of 56 patients were reviewed. The unoperated eye in unilateral cases was used as the control group. The mean age at surgery was 5.1...

Delays in oral cancer

This is a review from Canada where they attempt to relate the delays in oral cancer presentation to treatment and the impact on stage, diagnosis and survival. They recognise that potentially the most significant delay is between the patient first...

Surgical management of refractory osteoradionecrosis

This is a French single-centre, 10-year experience of 55 surgical resection and reconstruction procedures. They claim an overall effectiveness rate of 92.3%. Thity-six segmental and 19 marginal mandibulectomies were performed. A variety of free flaps were used with soft tissue...

Ablepharon-macrostomia syndrome

The ablepharon-macrostomia syndrome is a very rare condition caused by a dominant mutation in the TWIST2 gene. Congenital defects include rudimentary eyelids, macrostomia, ambiguous genitalia and campodactyly. Neonates are at risk of severe corneal exposure without intervention. Previous reports have...

A new autologous flap option for breast reconstruction

The authors of this paper present the first meaningful series utilising the lateral thigh perforator flap for breast construction. Eight patients had delayed unilateral reconstruction, each with two stacked flaps. Anastamoses were performed antegrade and retrograde to one internal mammary...