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Botulinum toxin (BoNT) for depression: A review of the mechanism of action and its potential place as an adjuvant treatment

BoNT is becoming a recognised efficient treatment for depression, endorsed by several disciplines including psychiatry. Clare Amrani examines the potential mechanism of action and explores the appropriate place of BoNT in the therapeutic armamentarium for depression. How did BoNT become...

Technology for remote working and COVID-19 resources

The COVID-19 pandemic has altered every aspect of how we live, and how healthcare needs to be provided for the welfare of patients and staff. I thought I would try to summarise a few potential technology tools that could be...

An overview of chemical peels

Chemical peels form an important part of most aesthetic and cosmetic practices. They are an affordable procedure for patients and significant results can be achieved. Generally chemical peels are a safe procedure, but only if used correctly and with caution....

Soft tissue augmentation – a review

The author explains how treating the face as a 3D structure is key to a good result with invasive or non-invasive procedures. History Rejuvenation of the face and trying to reverse the effects of ageing dates back centuries. Facial volume...

New IPL technology as treatment for melasma

Background Melasma is an acquired refractory pigmented skin disease. It is a complex multifactorial disorder and its pathogenesis has not yet been fully elucidated. Risk factors include genetic predisposition, sun exposure, stress, medications, and pregnancy. Melasma is divided into three...

How I Do It - Skin tightening with bipolar radiofrequency system

Skin tightening procedures occupy an important place in the practice of aesthetic medicine. Physicians have a big choice of energy-based devices (EBD) and sometimes it is difficult to find the right one. Profound Personally, I prefer to use Profound which...

How I Do It - Mesotherapy in combination with chemical peel

Photo-ageing, pigmentation, acne or rosacea can all have a significant impact on self-confidence and the overall quality of life. BioRePeelCl3 is a patented biphasic technology product based on 35% trichloroacetic acid, which allows safe and effective redermalisation and skin rejuvenation...

Perceptions and Deceptions a personal blog by the editor 19 May 2016

Should we be astonished to hear that the Right Honourable Jeremy Hunt, the Health Secretary who has created the greatest manpower crisis in the NHS in the past fifty years should now say that he is not actually an academic...

Gross Negligence Manslaughter in Healthcare: The medico-legal dilemma (part 10) – Informed consent (ii)

In the context of medicine, we typically speak of informed consent as having both an ethical and a legal basis. The ethics are related to patient autonomy and human rights. The legal perspective relates to the definition of what occurs if consent is not obtained, and a physical intervention occurs (assault or battery at a minimum and it would appear, gross negligence if things go wrong).

The future and a summary of the past

From liposuction to adipose stem cells; from regenerative medicine to tissue engineering; and a vision of the future. Part 3 Adipose stem cells There is a major clinical need for strategies that adequately reconstruct the soft tissue defects after deep...

Mercy Mission: all aboard with Mercy Ships off the coast of West Africa

Countries along the coast of West Africa are amongst the poorest in the world. Extreme levels of poverty often lead to poor outcomes or fatalities in many medical conditions that would be eminently treatable, with good outcomes in more developed...

Converse scalping flap for nasal reconstruction procedures

Case report This 78-year-old gentleman underwent excision of basal cell carcinoma overlying the left alar, nasal tip and nasal dorsum. The Converse scalping flap was raised and used to cover the defect. Non-adherent dressing was applied to provide temporary cover...