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How I Do It - Non-surgical skin cancer treatment: topical photodynamic therapy
The incidence of skin cancer is rising exponentially in the UK; in particular non-melanoma skin cancer, yet the current statistical data surrounding exact figures is thought to be underestimated. Topical photodynamic therapy (PDT) provides a non-invasive, safe and efficacious modality...Focus on Cosmeceuticals: Skin anatomy and photoageing
Skin anatomy The skin of the face provides crucial functions of temperature regulation, reparative functions following injury, facial expression, protective mechanisms against infection and ultraviolet radiation, as well as sensory perception. The integument consists of two principle layers, the epidermis...
Lymph node ratio in tongue cancer
This is an analysis of 88 patients treated in Switzerland between 2003 and 2012. All patients had a selective neck dissection and recurrence occurred in 25 patients. Overall and disease specific survival were 72% and 80%. They specifically looked at...
Combined Vismodegib and Mohs surgery
This is a report of eight patients with locally advanced periocular basal cell carcinoma who were treated with Vismodegib prior to Mohs micrographic surgery. The rationale for the combined treatment plan was that long-term Vismodegib is poorly tolerated due to...
Significance of exterior capsular spread in a clinically negative neck
This is a retrospective paper from Zagreb of 61 patients with a clinically T1-T3 N0 squamous cell carcinoma undergoing primary surgical treatment. All patients had a level I-IIII/IV elective neck dissection. Those who had adverse histological features, including extracapsular spread,...
Evidence based review of management for common head and neck cancers
As part of the PRS evidence based review series, this well written review summarises the up-to-date knowledge regarding the surgical and non-surgical management of the common facial skin cancers. The review is limited to BCC, SCC, MM and Merkel Cell...The First World War and the Development of Facial Surgery
Facial surgery has a history stretching to antiquity, but its success depended on luck until medical science had advanced enough to deal with three major issues – infection, surgical shock from blood loss and good anaesthesia. It was not until...
PRP and Microneedling in Aesthetic Medicine
Platelet rich plasma (PRP) makes sense scientifically. Platelets are a bit like biological robots. They do not have a cell nucleus, but they do have a program which directs them to surveil blood vessel walls and, in particular, to respond...
A review of reconstruction of the burned ear
The exposed location of the ear, combined with its thin skin and subcutaneous tissue makes it prone to full thickness burn injuries. As a result, deformity and disfigurement of the ear is a common sequelae of burns. This is a...
