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Stem cells in reconstructive surgery: a bright but cautious future

Regenerative medicine using stem cell technology is slowly becoming a reality in routine clinical practice especially in the field of tissue regeneration [1]. It is therefore not surprising that stem cell technology is starting to be of interest in reconstructive...

Exosomes: everything you always wanted to know and questions to ask your exosome provider

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. What are exosomes? Exosomes are just one subset of extracellular vesicles (EVs),...

Tissue engineered flaps

This article provides a thorough summary of the current techniques available in head and neck reconstruction. It details the challenge of restoration of form and function posed by the shape of the craniofacial skeleton and soft tissue. The introduction on...

PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

New recombinant human BMP for augmentation of the floor of the maxillary sinus

There has been a recent interest in the use of bone morphogenetic protein-7 (rhBMP-7) to augment the floor of the maxillary sinus. Loss of teeth in the posterior maxilla results in rapid horizontal and vertical reabsortion of alveolar bone because...

What to look for in new exosome products: A guide to the exosome cosmetic market

Exosomes have become increasingly trendy in the cosmeceutical market, not only as the latest buzzword but also in alignment with the growing trend towards natural beauty. By harnessing the regenerative potential of exosomes and incorporating them into daily skincare routines...

Aesthetics and Functionality in Ear Reconstruction

Recent years have brought important refinements to the approach and techniques of functional and aesthetic ear reconstruction. Aesthetics and Functionality in Ear Reconstruction by R Staudenmaier is an excellent book providing concise but detailed overview on the state of the...

The development of PDO threadlifting in the UK

Dr Jacques Otto looks at the development of polydioxanone (PDO) threads as an anti-ageing treatment, the creation of the Association of Polydioxanone Threads (APDOT) UK and what the future holds for threadlifting in the UK. Up to early 2014 the...

Oral supplementation for skin health and rejuvenation

Lauren Jamieson explores the increasing evidence behind the role of supplements in skin health – an exciting development in the world of aesthetic medicine. The fact that lifestyle factors – and diet most especially – have a profound influence on...

How I Do It - Scar treatment with sequential combination of short full beam and photo-acoustic fractional 1064nm QS laser

Wound healing takes place by two distinct mechanisms. The first involves cellular proliferation and migration resulting in regeneration. This occurs in the epidermis and leaves no scarring. The dermis is a collagen-rich connective tissue and when this is damaged the...

The uses of BTX-A in maxillofacial surgery

Botulinum toxin type A has many uses in maxillofacial surgery. This article will cover its uses in the treatment of Frey’s syndrome, myofascial pain, masseteric muscle hypertrophy and sialorrhoea. Other uses relevant to maxillofacial practice but not covered in this...

Cord lining mesenchymal stem cell exosomal proteins and their effects on hair follicles

Umbilical cord lining (UCL) mesenchymal stem cells (MSC) produce proteins and growth factors that, when packaged into exosomes in fixed proportions, can stimulate repair and regeneration in recipient cells. The pleiotropic properties of UCL-MSC have been shown to be effective...