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The use of platelet-rich plasma in skin flap grafts

This study was conducted to evaluate the ability of platelet rich plasma (PRP) to stimulate angiogenesis following skin flaps graft surgery, and its effect on flap survival rate. The use of PRP to improve the quality of bone regeneration and...

Electrochemotherapy for BCCs

A remarkable account of an effective non-surgical treatment for basal cell carcinomas (BCCs). Electrochemotherapy (ECT) consists of making the area surrounding the lesion temporarily permeable using electric pulses (under local anaesthesia), then bleomycin is administered to the area. The treatment...

ABG Lab takes Mesotherapy to pioneering new levels with innovative skin rejuvenation treatments

A US company, developer, and creator of innovative technologies for aesthetic medicine, anti-aging therapy, and skin rehabilitation, has taken Mesotherapy, the minimally invasive injection treatment, to pioneering new levels, by developing a range of intradermal injectables for the cellular renewal of skin, aesthetic facial remodeling and hair loss.

History of fat grafting

Fat grafting was first described in 1893 by Gustav Neuber, who transplanted adipose tissue from the arm to the orbit to correct depressed scars resulting from osteomyelitis. In 1895, Czerny reported excising a lipoma and grafting it into a breast...

Excisional margins for cutaneous malignancies

The authors present the results of a retrospective study of 495 non melanoma skin cancer (NMSC) lesions of the face treated with Mohs micrographic surgery (MMS) over a six year period. The size of the lesion was calculated as the...

New approaches to soft tissue reconstruction involving adipose tissue engineering

Introduction The spectrum of patients affected by subcutaneous tissue loss is both wide and varied, including those who have undergone tumour removal, trauma patients, such as those injured in road traffic accidents, and individuals who have suffered from deep burns...

The future and a summary of the past

From liposuction to adipose stem cells; from regenerative medicine to tissue engineering; and a vision of the future. Part 3 Adipose stem cells There is a major clinical need for strategies that adequately reconstruct the soft tissue defects after deep...

Risk factors for loco regional recurrence for oral SCC

Over a quarter of a million cases of oral squamous cell carcinomas (SCC) are diagnosed annually worldwide with 128,000 registered deaths. In spite of much-improved anaesthetic and surgical techniques, survival rates have not improved much over the past three decades....

A possible role for adipose tissue-derived stem cells in modulation of keloid scarring

Keloid scarring remains a challenging clinical problem due to both resistance to treatment as well as high rates of recurrence. Research into possible treatments is also hindered by keloid scarring being a uniquely human phenomenon. Recent evidence supports a role...

Prednisolone and/or acyclovir for Bell’s palsy

Facial nerve paralysis as a consequence of Bell’s palsy can result in devastating long‑term effects on a patient’s appearance. What is the best medical treatment for this condition? Stuart Burrows provides his appraisal of this landmark paper from the New...

Lymph node ratio – another predictor of outcomes in tongue SCC

Oral squamous cell carcinoma (SCC) is an increasing disease with over 263,000 diagnosed new cases and 128,000 deaths annually worldwide. Although there have been significant advances in diagnostics, surgery and anaesthetics there has been no increase in the survival rates...

The future of energy-based devices: do we have limits?

Victor Gabriel Clatici asks what is the final frontier in dermatology, plastic surgery and aesthetic medicine?