You searched for "carcinoma"

63 results found

Combined Vismodegib and Mohs surgery

This is a report of eight patients with locally advanced periocular basal cell carcinoma who were treated with Vismodegib prior to Mohs micrographic surgery. The rationale for the combined treatment plan was that long-term Vismodegib is poorly tolerated due to...

Significance of exterior capsular spread in a clinically negative neck

This is a retrospective paper from Zagreb of 61 patients with a clinically T1-T3 N0 squamous cell carcinoma undergoing primary surgical treatment. All patients had a level I-IIII/IV elective neck dissection. Those who had adverse histological features, including extracapsular spread,...

Outcomes of heavily pre-treated oral squamous cell carcinomas

Oral squamous cell carcinoma is one of the more common cancers worldwide. Surgery is the mainstay of treatment and often these patients have had adjuvant therapies. In spite of improving five year survival rates, local recurrent progressive disease is still...

Lymph node ratio – another predictor of outcomes in tongue SCC

Oral squamous cell carcinoma (SCC) is an increasing disease with over 263,000 diagnosed new cases and 128,000 deaths annually worldwide. Although there have been significant advances in diagnostics, surgery and anaesthetics there has been no increase in the survival rates...

Postoperative delirium

This is a retrospective study from Japan analysing 102 patients who underwent oral cancer resection and free flap reconstruction. Postoperative delirium occurred in a third of these patients. An increased risk was identified in those with high preoperative albumin, postoperative...

How I Do It - Non-surgical skin cancer treatment: topical photodynamic therapy

The incidence of skin cancer is rising exponentially in the UK; in particular non-melanoma skin cancer, yet the current statistical data surrounding exact figures is thought to be underestimated. Topical photodynamic therapy (PDT) provides a non-invasive, safe and efficacious modality...

Non-surgical management of actinic keratosis, Bowen’s disease and non-melanoma skin cancer

Non-melanoma skin cancers (NMSCs) are primary cutaneous neoplasms comprising mainly of basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs). In 2011, 102,628 cases of NMSCs (74% BCC and 23% SCC) were recorded in England, making NMSC the most common...

Submental island flap to reconstruct the lower lip

The lips are necessary for oral competence, cosmesis, speech and feeding. Non melanoma cancers can affect the lips, and the lower lips are about 80% more likely to be affected. A large number of these cancers are squamous cell carcinomas....

The lateral neck cystic mass – diagnostic dilemma

Solitary cystic masses in the lateral neck can present a significant diagnostic dilemma. These cystic masses often develop in young adults distinguishing a branchial cleft cyst from a cystic lymph node with imaging and even high-quality fine needle aspiration cytology...

Complications of plates in fibula free flaps

Good functional reconstruction of the mandible remains challenging for the maxillofacial surgeon. The fibula osteocutaneous flap is widely used as a method of mandibular reconstruction and it can withstand multiple osteotomies and a thus requires hardware to adapt and hold...

Clinical histopathology of 250 parotidectomy patients

This is a retrospective study of 250 consecutive parotidectomy patients at units in Belgium and the Netherlands. The sensitivity and specificity of FNAC was 64% and 99% respectively. The sensitivity being slightly lower than the often quoted 80%. MRI and...

Another paper advocating resection templates

Resection in the head and neck region leads to complex defects with significant impairment in function. Reconstruction is even more difficult and to improve the accuracy of both resection and reconstruction a number of aids are used. With the improved...