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Botulinum toxin (BoNT) for depression: A review of the mechanism of action and its potential place as an adjuvant treatment

BoNT is becoming a recognised efficient treatment for depression, endorsed by several disciplines including psychiatry. Clare Amrani examines the potential mechanism of action and explores the appropriate place of BoNT in the therapeutic armamentarium for depression. How did BoNT become...

Immediate versus delayed post mastectomy breast reconstruction

The authors review and analyse the current literature comparing the psychosocial outcomes of immediate versus delayed post mastectomy breast reconstruction. Breast cancer is the most prevalent cancer in women and has a lifetime incidence of one in nine. Mastectomy may...

Perspectives on: Polyurethane covered breast implants

The manufacturer’s viewpoint: Myths, failures and the regulation of the modern breast implant. The modern day silicone breast implant industry was created with the Dow Corning prosthesis, first used in the USA in 1962. Since its introduction into the market...

Gross Negligence Manslaughter in Healthcare: The medico-legal dilemma (part 3)

14 June 2021 is the day in the Chinese calendar to celebrate the Dragon Boat Festival. These local holidays are a reminder of the deep cultural heritage enjoyed by the Chinese people.

An anecdotal and historical review of the median forehead flap

The specialty of plastic surgery has roots stretching back centuries. Here HS Adenwalla, renowned cleft surgeon, provides a fascinating account of the development of the median forehead flap. In the early 1970s a young boy of 16-years-old was brought to...

Cord lining mesenchymal stem cell exosomal proteins and their effects on hair follicles

Umbilical cord lining (UCL) mesenchymal stem cells (MSC) produce proteins and growth factors that, when packaged into exosomes in fixed proportions, can stimulate repair and regeneration in recipient cells. The pleiotropic properties of UCL-MSC have been shown to be effective...

First there was Sophia

A robot is a man-made machine which can do some things by itself. It is not alive. It has no physiology. But it does have a source of energy, sensors to interact with the external world, a rudimentary nervous system...

­Immediate planned reconstruction following complex craniofacial reconstruction

The immediate reconstruction of 3-D craniofacial defects is extremely difficult and can be more difficult than the ablation. Perfect shape and symmetry is required. In the past decade this has largely improved with CAD/CAM engineering. The authors report a one-step...

A guide to hair transplantation

A leading hair transplant surgeon provides an overview of the most effective surgical treatments for hair restoration – and how the industry will develop over the next decade. Modern hair transplant techniques were first developed in Japan in the 1930s...

Factors influencing a career choice in plastic surgery as a UK medical student

The medical school curriculum is increasingly focusing on the role of a general practitioner, which has resulted in medical students having reduced exposure to surgical specialties. There has been a longstanding concern that plastic surgery teaching and exposure in the...

In conversation with Emanuele Bartoletti (2024)

We were delighted to catch up with Dr Emanuele Bartoletti, President of Società Italiana di Medicina Estetica (SIME), about the latest news from the society. You have been involved with SIME for many years now; what have been the highlights...

In conversation with Klaus Fritz

We spoke with Dr Klaus Fritz, a board member with 5CC, about his career in dermatology and 5CC’s upcoming congress in Barcelona. Can you tell us a little bit about what led you into the field of dermatology, and what...