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Extracutaneous Merkel cell carcinoma or metastatic Merkel cell carcinoma with an occult primary?

Merkel cell carcinoma (MCC) is a rare and aggressive malignancy arising from dermal neuroendocrine cells, first described by Toker in 1972 [1]. It is predominately seen in the head and neck region of older, white males and risk factors include...

Focus on Cosmeceuticals: Skin anatomy and photoageing

Skin anatomy The skin of the face provides crucial functions of temperature regulation, reparative functions following injury, facial expression, protective mechanisms against infection and ultraviolet radiation, as well as sensory perception. The integument consists of two principle layers, the epidermis...

Clitoral reconstructive surgery after female genital cutting

Female genital mutilation / cutting (FGM/C), aka female circumcision, is defined by the World Health Organization (WHO) as “All procedures that involve partial or total removal of the external female genitalia for non-medical reasons” [1]. Practised in Africa and other...

The development of PDO threadlifting in the UK

Dr Jacques Otto looks at the development of polydioxanone (PDO) threads as an anti-ageing treatment, the creation of the Association of Polydioxanone Threads (APDOT) UK and what the future holds for threadlifting in the UK. Up to early 2014 the...

Off-label cosmetic use of botulinum toxin in the lower face

Botulinum toxin A (BoNTA) is commonly used as an off-label cosmetic modality to improve the ageing lower face and neck, and may be used as a single line treatment or in combination with other procedures, such as dermal fillers [1]....

The Evolution of Wood MediSpa

As surgeons we must have all dreamt of owning our own facility. The perfect dream of a stand-alone private hospital with the entire patient journey seamlessly mapped out. It would offer unparalleled continuity of care – the same team doing...

Recent developments in facelift surgery

Early facelifting procedures were documented in the 1900s, where skin undermining with excess skin excision along the hairline was performed. The 1970s witnessed a major change with an upsurge in public interest in facelift surgery, which led to innovative changes...

Raising the bar for safer cosmetic surgery in the UK – part 1

In part one of a two-series article Professor James Frame, from the Anglia Ruskin University, gives us his opinion on what needs to be done to improve cosmetic surgery and patient safety in the UK. Cosmetic surgery is most easily...

What to look for in new exosome products: A guide to the exosome cosmetic market

Exosomes have become increasingly trendy in the cosmeceutical market, not only as the latest buzzword but also in alignment with the growing trend towards natural beauty. By harnessing the regenerative potential of exosomes and incorporating them into daily skincare routines...