Journal Reviews
Medical treatment of orbital lymphatic malformations
This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...
CD73 in aggressive basal cell carcinoma
This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...
Less extrusion of StopLoss Jones Tubes
This is a retrospective comparison of the survival of StopLoss Jones tubes with conventional Lester Jones tubes. Between 2014 and 2016, 31 StopLoss and 59 Lester-Jones tubes were inserted. The authors compared the extrusion and sinking-in rates between the StopLoss...
Diagnosis and management of solitary fibrous tumour
This is a retrospective review of 21 patients diagnosed with solitary fibrous tumour of the orbit between 1996 and 2018 at a single centre. The authors reviewed the clinical presentation, management and course of the disease and reanalysed the histopathology...
Vitamin D and thyroid eye disease
This is a retrospective review of vitamin D levels in patients with thyroid eye disease (TED). Vitamin D levels in 89 patients with Grave’s disease and TED were compared against 89 patients with Grave’s disease and no TED. They also...
Ablepharon-macrostomia syndrome
The ablepharon-macrostomia syndrome is a very rare condition caused by a dominant mutation in the TWIST2 gene. Congenital defects include rudimentary eyelids, macrostomia, ambiguous genitalia and campodactyly. Neonates are at risk of severe corneal exposure without intervention. Previous reports have...
Maximising the results of blepharoplasty
The aesthetic anatomy of lower eyelid is detailed leading to discussion of operative technique to achieve the goals of blepharoplasty; for the lower lid these are a youthful lid cheek junction, a positive canthal tilt and no scleral show. The...
Radiotherapy for orbital apex cavernous haemangiomas
This is a review of six patients with cavernous venous malformations (haemangiomas) involving the orbital apex who were treated with fractionated stereotactic radiotherapy. Patients were diagnosed on MRI imaging with only one having had previous surgery to debulk the lesion....
Congenital ptosis and astigmatism
This is a review of the effect of congenital ptosis surgery on refractive error. Seventy-one eyes of 56 patients were reviewed. The unoperated eye in unilateral cases was used as the control group. The mean age at surgery was 5.1...
Thyroid eye disease and obstructive sleep apnoea
This is a retrospective study looking for an association between compressive optic neuropathy in thyroid eye disease (TED-CON) and obstructive sleep apnoea (OSA). One hundred and nine patients with thyroid eye disease were asked to complete a validated questionnaire designed...
Cavernous sinus thrombosis and orbital cellulitis
This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...
Corneal neurotisation with an allograft
This is the first reported use of an acellular nerve allograft for corneal neurotisation. Seven patients received a 7cm long commercially prepared acellular nerve allograft. This was coapted to a functioning supratrochlear, supraorbital or infraorbital nerve and then tunnelled to...
